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Monthly Archives: April 2017

Quora contributions from August 2016 to March 2017

Quora is a question-and-answer site. You can view all my contributionsĀ here; selected highlights are listed below. I encourage you to check out the other answers submitted for each question, too!

Epigenetics

What molecular mechanisms regulate methylase activity?

Why is the epitranscriptome (epigenetic marks on mRNA) important when mRNA molecules last so transiently?

What is the difference between histones and nucleosomes?

What’s ā€œHistone modification”?

What is the difference between acetylation and methylation?

Why does acetylation remove the positive charge on histones?

Why does trimethylation of histone H3 on lysine 27 (K27) result in chromatin repression?

Should histone modifications be labeled as an epigenetic modification? Or just a chromatin modification?

Are epigenetics a type of post-translational modification?

Could stem cells just be epigenetic?

I want to start learning about epigenetics. Where should I start?

What are the best books on epigenetics, for a layperson?

Cancer

Can cancer cells evolve resistance to treatment?

Why are familial tumors usually multiple compared to sporadic cases, even when the same mutation is responsible for both types?

Why can’t people with cancer donate their organs?

Viruses

Can we use mRNA silencing techniques to inhibit the HIV genome?

Other scientific topics

Once we insert a desired gene into the human genome, how is its expression limited to the specific target organs where the gene is needed?

Do our parents have the same DNA as us?

Do red blood cells have functional miRNAs?

My ex-husband and I both have blood type O (positive and negative). How is it possible that our son has type B+?

Miscellaneous

Do you think Goodreads should ask a few questions from a book before letting anyone rate it?