RSS

Category Archives: Books

Reviews of “Introducing Epigenetics: A Graphic Guide”

My book‘s been out for a few months now, so I thought I’d share a couple of my favourite reviews so far!

Here’s a video review from Amanda, aka @TangibleAnsible, from the “A Scientist Reads” YouTube channel:

The second review is from The Epigenetics Literacy Project, a website that connects journalists and the public to the latest epigenetics news:

Many do not realize or appreciate the awkward phase epigenetics is in and thus they are prone to misunderstanding or misstating findings in the field. But Ennis does an excellent job of explaining how epigenetics fits in as a subset of the fields of molecular biology and gene regulation. In fact, in the first ten pages, epigenetics and epigenetic changes are sparsely discussed, which should emphasize to the reader that this science has not trumped previous dogma on gene activity. Epigenetics is merely a piece of a larger puzzle.

The reality is that there is a broad spectrum of opinions about epigenetics, ranging from the purely pseudoscientific (e.g. your thoughts can stop or give you cancer) to believing the field to have little significance in the grand scheme of gene regulation to believing the theory of evolution needs to be rewritten because of epigenetics. Ennis does not shy away from some of these controversial ideas but does make sure to place the appropriate disclaimers.

You can read the full review here.

If you’ve read and enjoyed Introducing Epigenetics, please consider leaving your own review on Goodreads or your favourite book vendor’s site!

(Speaking of book vendors, a note to Canadian readers: there’s been some kind of glitch with the Canadian supply of the book, which the publisher is trying to resolve. Amazon.ca are still listing the book as “Temporarily out of stock” and my friendly local independent bookstore have also had problems trying to order it from their usual Canadian supplier, but you can order it online from Chapters or from a US site. It’s also available as an e-book, but to be honest I think the illustrations work better in the hard copy version).

Advertisements
 

Quora contributions from August 2016 to March 2017

Quora is a question-and-answer site. You can view all my contributions here; selected highlights are listed below. I encourage you to check out the other answers submitted for each question, too!

Epigenetics

What molecular mechanisms regulate methylase activity?

Why is the epitranscriptome (epigenetic marks on mRNA) important when mRNA molecules last so transiently?

What is the difference between histones and nucleosomes?

What’s “Histone modification”?

What is the difference between acetylation and methylation?

Why does acetylation remove the positive charge on histones?

Why does trimethylation of histone H3 on lysine 27 (K27) result in chromatin repression?

Should histone modifications be labeled as an epigenetic modification? Or just a chromatin modification?

Are epigenetics a type of post-translational modification?

Could stem cells just be epigenetic?

I want to start learning about epigenetics. Where should I start?

What are the best books on epigenetics, for a layperson?

Cancer

Can cancer cells evolve resistance to treatment?

Why are familial tumors usually multiple compared to sporadic cases, even when the same mutation is responsible for both types?

Why can’t people with cancer donate their organs?

Viruses

Can we use mRNA silencing techniques to inhibit the HIV genome?

Other scientific topics

Once we insert a desired gene into the human genome, how is its expression limited to the specific target organs where the gene is needed?

Do our parents have the same DNA as us?

Do red blood cells have functional miRNAs?

My ex-husband and I both have blood type O (positive and negative). How is it possible that our son has type B+?

Miscellaneous

Do you think Goodreads should ask a few questions from a book before letting anyone rate it?

 

 

 

 

“Introducing Epigenetics: A Graphic Guide” now available in the UK!

I’m delighted to announce that my book was published today in the UK!

I received a few advance copies on Tuesday, and I’m really pleased with how it’s turned out.

fullsizeoutput_3e8

Pocket-sized!

fullsizeoutput_3ec

This is one of my favourite illustrations (although it’s hard to choose! Oliver Pugh did a fantastic job). I did my postdoctoral research on repetitive DNA, and I think RNA is one of the most interesting molecules of all time, so I might be a bit biased though.

I’ve also set up my author profile page on Goodreads.

The book is available for pre-order everywhere, and will be published on March 14th in the USA and March 20th in Canada and elsewhere. Links to all major vendors can be found here – or ask your friendly local independent bookstore!

 
Leave a comment

Posted by on 2017/02/02 in Books, epigenetics

 

Announcing “Introducing Epigenetics: A Graphic Guide” – coming in early 2017!

INTRODUCING-EPIGENETICS-14mm new1I’m very excited to officially announce that I have a new book coming out next year!

“Introducing Epigenetics” is part of the Graphic Guides series by Icon Books. I’ve written the text, and artist Oliver Pugh is currently working on the illustrations. He’s done great work on earlier books in the series, and I can’t wait to see his artwork for Introducing Epigenetics!

The book covers all aspects of the exciting field of epigenetics, from the basics of gene regulation and embryonic development to the role of epigenetic modifications in diseases and their treatment, evolution, and the controversial field of epigenetic inheritance. I had a ton of fun writing it, even though it didn’t leave me with much time to do anything else last year!

The book will be available on February 2nd in the UK and March 14th in Canada, Australia, and the US. Other countries TBD.

More details, including links to online vendors, available here.

 

 
2 Comments

Posted by on 2016/08/13 in Books, epigenetics